Keysight’s 7500 inverted light microscope (ILM) system combines the power of a high-resolution atomic force microscope (AFM) with the direct optical viewing capability of an inverted optical microscope.

The Keysight ILM offers unparalleled performance and ease of use for imaging in fluids. It extends AFM utility in order to encompass studies of single molecules, polymers, cell membranes, whole cells, and much more. Atomic force and optical (or fluorescence) microscopy data can be obtained simultaneously with the Keysight ILM.

The rigid stage structure provides the low noise floor needed to obtain sub-nanometer resolution. Furthermore, the advanced design allows the AFM to sit on top of an inverted microscope and under the illumination pillar, resulting in better optical contrast for the images.

Keysight’s QuickSlide sample-loading mechanism and a flexible sample-handling plate makes sample preparation easy. The AFM is mounted on the QuickSlide assembly, allowing the user to change samples and/or solutions without affecting the alignment of the AFM or the optical microscope.